| Gene Information | |
|---|---|
| Gene Name | MT3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 68 |
| Protein Names | Metallothionein-3 (MT-3) (GIFB) (GIF) (Growth inhibitory factor) (Metallothionein-III) (MT-III) |
| Target Name | metallothionein-3 |
| Target Type | NA |
| Gene Age | 424 ( ENSG00000087250 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | P25713 |
| Gene Card | MT3 |
| Uniprot ID | P25713 |
| Pfam | PF00131 |
| In ASD | no |
| Allosteric Prediction | no (-0.66528529) |
| Ortholog in Animals | Alpaca_ MT3 ( ortholog_one2one ) Alpaca_ MT2A ( ortholog_one2one ) Dog_ MT3 ( ortholog_one2one ) GuineaPig_ MT3 ( ortholog_one2one ) Macaque_ MT3 ( ortholog_one2one ) Pig_ MT3 ( ortholog_one2one ) Rat_ Mt3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | MT1H, MT1G, MT1F, MT1X, MT1M, MT2A, MT1A, MT1E, MT1HL1, MT1B, MT4 |
| Tissue | brain, cerebral.cortex, adrenal.gland |
| Tissue Specificity | Abundant in a subset of astrocytes in the normal human brain, but greatly reduced in the Alzheimer disease (AD) brain. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 2F5H (NMR - ) 2FJ4 (NMR - ) 2FJ5 (NMR - ) |
| DBSNP | NA |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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