| Gene Information | |
|---|---|
| Gene Name | ASGR2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 311 |
| Protein Names | Asialoglycoprotein receptor 2 (ASGP-R 2) (ASGPR 2) (C-type lectin domain family 4 member H2) (Hepatic lectin H2) (HL-2) |
| Target Name | asialoglycoprotein receptor 2 |
| Target Type | NA |
| Gene Age | 132 ( ENSG00000161944 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P07307 |
| Gene Card | ASGR2 |
| Uniprot ID | P07307 |
| Pfam | PF00059 |
| In ASD | no |
| Allosteric Prediction | yes (0.061555141) |
| Ortholog in Animals | Alpaca_ ASGR2 ( ortholog_one2one ) Dog_ ASGR2 ( ortholog_one2one ) GuineaPig_ ASGR2 ( ortholog_one2one ) Macaque_ ASGR2 ( ortholog_one2one ) Mouse_ Asgr2 ( ortholog_one2one ) Pig_ ASGR2 ( ortholog_one2one ) Rat_ Asgr2 ( ortholog_one2one ) Rabbit_ ASGR2 ( ortholog_one2one ) |
| Ohnologs | CLEC6A |
| Paralogs | ASGR1, CLEC4G, CLEC4C, CLEC4M, CLEC17A, CLEC4A, CLEC4F, CLEC10A, CLEC6A, FCER2, CD209, CLEC4D, CD207, CLEC4E |
| Tissue | liver |
| Tissue Specificity | Expressed exclusively in hepatic parenchymal cells. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2304978 |
| Subcellular location [CC] | Membrane; Single-pass type II membrane protein. |
| Mouse PG classification | NA |
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