| Gene Information | |
|---|---|
| Gene Name | MT-ND2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 347 |
| Protein Names | NADH-ubiquinone oxidoreductase chain 2 (EC 7.1.1.2) (NADH dehydrogenase subunit 2) |
| Target Name | nadh-ubiquinone oxidoreductase chain 2 |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000198763 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | P03891 |
| Gene Card | MT-ND2 |
| Uniprot ID | P03891 |
| Pfam | PF06444; PF00361 |
| In ASD | no |
| Allosteric Prediction | no (-0.286798564) |
| Ortholog in Animals | Alpaca_ ND2 ( ortholog_one2one ) Alpaca_ MT-ND2 ( ortholog_one2one ) GuineaPig_ ND2 ( ortholog_one2one ) Macaque_ ND2 ( ortholog_one2one ) Mouse_ mt-Nd2 ( ortholog_one2one ) Pig_ ND2 ( ortholog_one2one ) Rat_ Mt-nd2 ( ortholog_one2one ) Rabbit_ ND2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | MT-ND4, MT-ND5 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.376654(Chimpanzee);0.344972(Mouse);0.643264(Rat);0.265395(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5XTC (EM 3.70A ) 5XTD (EM 3.70A ) 5XTH (EM 3.90A ) 5XTI (EM 17.40A ) |
| DBSNP | rs1117207 rs41510547 rs1556422884 rs267606889 rs201854167 rs1556422903 rs28357980 rs879058895 rs28357984 rs199476115 rs1603219855 rs41320049 rs878853115 rs3020601 rs3021088 rs1603219973 |
| Subcellular location [CC] | Mitochondrion inner membrane {ECO:0000250|UniProtKB:P03892}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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