| Gene Information | |
|---|---|
| Gene Name | MT-CO3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 261 |
| Protein Names | Cytochrome c oxidase subunit 3 (EC 7.1.1.9) (Cytochrome c oxidase polypeptide III) |
| Target Name | cytochrome c oxidase subunit 3 |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000198938 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | P00414 |
| Gene Card | MT-CO3 |
| Uniprot ID | P00414 |
| Pfam | PF00510 |
| In ASD | no |
| Allosteric Prediction | no (-0.422440405) |
| Ortholog in Animals | Alpaca_ COX3 ( ortholog_one2one ) Alpaca_ MT-CO3 ( ortholog_one2one ) GuineaPig_ COX3 ( ortholog_one2one ) Macaque_ COX3 ( ortholog_one2one ) Mouse_ mt-Co3 ( ortholog_one2one ) Pig_ COX3 ( ortholog_one2one ) Rat_ Mt-co3 ( ortholog_one2one ) Rabbit_ COX3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.220212(Chimpanzee);0.200376(Mouse);0.450509(Rat);0.107692(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5Z62 (EM 3.60A ) |
| DBSNP | rs1556423637 rs267606611 rs2853825 rs200613617 rs1556423753 rs200809063 |
| Subcellular location [CC] | Mitochondrion inner membrane {ECO:0000269|PubMed:30030519}; Multi-pass membrane protein {ECO:0000269|PubMed:30030519}. |
| Mouse PG classification | NA |
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