| Gene Information | |
|---|---|
| Gene Name | MT-CO2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 227 |
| Protein Names | Cytochrome c oxidase subunit 2 (EC 7.1.1.9) (Cytochrome c oxidase polypeptide II) |
| Target Name | cytochrome c oxidase subunit 2 |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000198712 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | P00403 |
| Gene Card | MT-CO2 |
| Uniprot ID | P00403 |
| Pfam | PF00116; PF02790 |
| In ASD | no |
| Allosteric Prediction | yes (0.659620825) |
| Ortholog in Animals | Alpaca_ COX2 ( ortholog_one2one ) Alpaca_ MT-CO2 ( ortholog_one2one ) GuineaPig_ COX2 ( ortholog_one2one ) Macaque_ COX2 ( ortholog_one2one ) Mouse_ mt-Co2 ( ortholog_one2one ) Pig_ COX2 ( ortholog_one2one ) Rat_ Mt-co2 ( ortholog_one2one ) Rabbit_ COX2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.364882(Chimpanzee);0.342404(Mouse);0.624989(Rat);0.259665(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3VRJ (X-ray 1.90A ) 5Z62 (EM 3.60A ) |
| DBSNP | rs199474827 rs1569484167 rs199474826 rs1116904 |
| Subcellular location [CC] | Mitochondrion inner membrane {ECO:0000269|PubMed:30030519}; Multi-pass membrane protein {ECO:0000269|PubMed:30030519}. |
| Mouse PG classification | NA |
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