| Gene Information | |
|---|---|
| Gene Name | MT-CO1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 513 |
| Protein Names | Cytochrome c oxidase subunit 1 (EC 7.1.1.9) (Cytochrome c oxidase polypeptide I) |
| Target Name | cytochrome c oxidase subunit 1 |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000198804 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | P00395 |
| Gene Card | MT-CO1 |
| Uniprot ID | P00395 |
| Pfam | PF00115 |
| In ASD | no |
| Allosteric Prediction | yes (0.767087947) |
| Ortholog in Animals | Alpaca_ COX1 ( ortholog_one2one ) Alpaca_ MT-CO1 ( ortholog_one2one ) GuineaPig_ COX1 ( ortholog_one2one ) Macaque_ COX1 ( ortholog_one2one ) Mouse_ mt-Co1 ( ortholog_one2one ) Pig_ COX1 ( ortholog_one2one ) Rat_ Mt-co1 ( ortholog_one2one ) Rabbit_ COX1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.368423(Chimpanzee);0.345210(Mouse);0.629515(Rat);0.269335(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5Z62 (EM 3.60A ) |
| DBSNP | rs281865417 rs267606883 rs370673798 rs28461189 rs2853818 rs199476127 rs199476126 rs368552121 rs372136420 rs267606884 |
| Subcellular location [CC] | Mitochondrion inner membrane {ECO:0000269|PubMed:30030519}; Multi-pass membrane protein {ECO:0000269|PubMed:30030519}. |
| Mouse PG classification | NA |
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