| Gene Information | |
|---|---|
| Gene Name | SHROOM3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1996 |
| Protein Names | Protein Shroom3 (Shroom-related protein) (hShrmL) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 886 ( ENSG00000138771 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q8TF72 |
| Gene Card | SHROOM3 |
| Uniprot ID | Q8TF72 |
| Pfam | PF08688; PF08687; PF00595 |
| In ASD | no |
| Allosteric Prediction | no (-1.295650013) |
| Ortholog in Animals | Alpaca_ SHROOM3 ( ortholog_one2one ) Dog_ SHROOM3 ( ortholog_one2one ) GuineaPig_ SHROOM3 ( ortholog_one2one ) Macaque_ SHROOM3 ( ortholog_one2one ) Mouse_ Shroom3 ( ortholog_one2one ) Rat_ Shroom3 ( ortholog_one2one ) |
| Ohnologs | SHROOM2 |
| Paralogs | SHROOM4, SHROOM2, SHROOM1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6FBB (X-ray 1.30A ) 6FCP (X-ray 1.45A ) |
| DBSNP | rs3821979 rs344140 rs344141 rs3733242 |
| Subcellular location [CC] | Cell junction, adherens junction {ECO:0000250|UniProtKB:Q9QXN0}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q9QXN0}. Apical cell membrane {ECO:0000250|UniProtKB:Q9QXN0}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q9QXN0}. Note=Colocalizes with F-actin in stress fibers and adherens junctions. {ECO:0000250|UniProtKB:Q9QXN0}. |
| Mouse PG classification | NA |
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