| Gene Information | |
|---|---|
| Gene Name | MEX3B |
| Organism | Homo sapiens (Human) |
| Gene Length | 569 |
| Protein Names | RNA-binding protein MEX3B (RING finger and KH domain-containing protein 3) (RING finger protein 195) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000183496 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q6ZN04 |
| Gene Card | MEX3B |
| Uniprot ID | Q6ZN04 |
| Pfam | PF00013 |
| In ASD | no |
| Allosteric Prediction | no (-1.000045803) |
| Ortholog in Animals | Alpaca_ MEX3B ( ortholog_one2one ) Dog_ MEX3B ( ortholog_one2one ) GuineaPig_ MEX3B ( ortholog_one2one ) Macaque_ MEX3B ( ortholog_one2one ) Mouse_ Mex3b ( ortholog_one2one ) Pig_ MEX3B ( ortholog_one2one ) Rat_ Mex3b ( ortholog_one2one ) Rabbit_ MEX3B ( ortholog_one2one ) |
| Ohnologs | MEX3C, MEX3D |
| Paralogs | MEX3A, MEX3D, MEX3C |
| Tissue | testis, brain |
| Tissue Specificity | Highest levels found in fetal brain and testis. Detected in the adult intestinal epithelium, specifically in goblet cell at protein level. {ECO:0000269|PubMed:17267406}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:18779327}. Cytoplasm {ECO:0000269|PubMed:18779327}. Cytoplasm, P-body {ECO:0000269|PubMed:18779327}. Cytoplasmic granule {ECO:0000269|PubMed:18779327}. Note=Predominantly expressed in the cytoplasm and shuttles between the cytoplasm and the nucleus through the CRM1 export pathway. Localization to P-bodies is dependent on 14-3-3. |
| Mouse PG classification | NA |
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