| Gene Information | |
|---|---|
| Gene Name | CDC73 |
| Organism | Homo sapiens (Human) |
| Gene Length | 531 |
| Protein Names | Parafibromin (Cell division cycle protein 73 homolog) (Hyperparathyroidism 2 protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000134371 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q6P1J9 |
| Gene Card | CDC73 |
| Uniprot ID | Q6P1J9 |
| Pfam | PF05179; PF16050 |
| In ASD | no |
| Allosteric Prediction | no (-0.007462272) |
| Ortholog in Animals | Alpaca_ CDC73 ( ortholog_one2one ) Dog_ CDC73 ( ortholog_one2one ) GuineaPig_ CDC73 ( ortholog_one2one ) Macaque_ CDC73 ( ortholog_one2one ) Mouse_ Cdc73 ( ortholog_one2one ) Pig_ CDC73 ( ortholog_one2one ) Rat_ Cdc73 ( ortholog_one2one ) Rabbit_ CDC73 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Found in adrenal and parathyroid glands, kidney and heart. {ECO:0000269|PubMed:15580289}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.014161(Rat);0.055709(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5YDE (X-ray 1.02A ) 5YDF (X-ray 1.40A ) 6TED (EM 3.10A ) 7OOP (EM 2.90A ) 7OPC (EM 3.00A ) 7OPD (EM 3.00A ) |
| DBSNP | rs1060500015 rs121434264 rs752383339 rs971586985 rs35590728 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:15580289, ECO:0000269|PubMed:15632063, ECO:0000269|PubMed:15923622}. |
| Mouse PG classification | LPG |
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