Gene Information
Gene NameMYPN
OrganismHomo sapiens (Human)
Gene Length1320
Protein NamesMyopalladin (145 kDa sarcomeric protein)
Target NameNA
Target TypeNA
Gene Age886 ( ENSG00000138347 )
Evolutionary StageVertebrata
AlphaFoldDBQ86TC9
Gene CardMYPN
Uniprot IDQ86TC9
PfamPF07679
In ASDno
Allosteric Predictionno (-1.378231654)
Ortholog in AnimalsAlpaca_ MYPN ( ortholog_one2one )
Dog_ MYPN ( ortholog_one2one )
GuineaPig_ MYPN ( ortholog_one2one )
Macaque_ MYPN ( ortholog_one2one )
Mouse_ Mypn ( ortholog_one2one )
Pig_ MYPN ( ortholog_one2one )
Rat_ Mypn ( ortholog_one2one )
Rabbit_ MYPN ( ortholog_one2one )
OhnologsPALLD
ParalogsPALLD, OBSCN, HMCN1, IGFN1, CCDC141, ALPK3, SPEG, SPEGNB, MYOT
Tissueheart, skeletal.muscle, artery, left.atrium, left.ventricle, mitral.valve, penis, pineal.gland, pulmonary.valve, tongue, tricuspid.valve
Tissue SpecificityExpressed in adult skeletal muscle and fetal heart. {ECO:0000269|PubMed:11309420}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs140148105  rs199476401  rs199476402  rs199476403  rs199476404  rs11596653  rs199476406  rs74143030  rs199476409  rs143338091  rs10823148  rs10997975  rs181355189  rs7916821  rs3814182  rs62620248  rs199476410  rs199476411  rs199476413  rs199476414  rs149887823  rs864621995  rs71584501  rs71534278  rs7079481  rs138313730  rs71534280  rs199476416  rs199476417 
Subcellular location [CC]Cytoplasm {ECO:0000269|PubMed:11309420}. Nucleus {ECO:0000269|PubMed:11309420}. Cytoplasm, myofibril, sarcomere {ECO:0000269|PubMed:11309420}. Cytoplasm, myofibril, sarcomere, Z line {ECO:0000269|PubMed:11309420, ECO:0000269|PubMed:28017374}. Note=Bound to sarcomere both at the Z-line periphery and in the central I-band region. {ECO:0000269|PubMed:11309420}.
Mouse PG classificationNA
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