| Gene Information | |
|---|---|
| Gene Name | HDGF |
| Organism | Homo sapiens (Human) |
| Gene Length | 240 |
| Protein Names | Hepatoma-derived growth factor (HDGF) (High mobility group protein 1-like 2) (HMG-1L2) |
| Target Name | hepatoma-derived growth factor |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000143321 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P51858 |
| Gene Card | HDGF |
| Uniprot ID | P51858 |
| Pfam | PF00855 |
| In ASD | no |
| Allosteric Prediction | yes (0.032267116) |
| Ortholog in Animals | Alpaca_ HDGF ( ortholog_one2one ) GuineaPig_ HDGF ( ortholog_one2one ) Macaque_ HDGF ( ortholog_one2one ) Mouse_ Hdgf ( ortholog_one2one ) Pig_ HDGF ( ortholog_one2one ) Rat_ Hdgf ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | HDGFL3, HDGFL2, PSIP1, HDGFL1 |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:7929202}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1RI0 (NMR - ) 2NLU (NMR - ) |
| DBSNP | rs4399146 |
| Subcellular location [CC] | [Isoform 1]: Nucleus {ECO:0000269|PubMed:11751870, ECO:0000269|PubMed:26845719}. Cytoplasm {ECO:0000269|PubMed:11751870}. Secreted, extracellular exosome {ECO:0000269|PubMed:27926477}. Note=Secreted by exosomes and is located inside the exosome (PubMed:27926477). May also be secreted as free protein via an as yet unknown pathway (PubMed:27926477). {ECO:0000269|PubMed:27926477}.; [Isoform 2]: Nucleus {ECO:0000269|PubMed:26845719}. Cytoplasm {ECO:0000269|PubMed:26845719}. Secreted, extracellular exosome {ECO:0000269|PubMed:27926477}. Note=Secreted by exosomes and is located on the outer exosome surface. {ECO:0000269|PubMed:27926477}.; [Isoform 3]: Nucleus {ECO:0000269|PubMed:26845719}. Cytoplasm {ECO:0000269|PubMed:26845719}. Secreted, extracellular exosome {ECO:0000269|PubMed:27926477}. Note=Secreted by exosomes and is located on the outer exosome surface. {ECO:0000269|PubMed:27926477}. |
| Mouse PG classification | NA |
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