| Gene Information | |
|---|---|
| Gene Name | MICAL |
| Organism | Homo sapiens (Human) |
| Gene Length | 1067 |
| Protein Names | [F-actin]-monooxygenase MICAL1 (EC 1.14.13.225) (EC 1.6.3.1) (Molecule interacting with CasL protein 1) (MICAL-1) (NEDD9-interacting protein with calponin homology and LIM domains) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q8TDZ2 |
| Gene Card | MICAL1 |
| Uniprot ID | Q8TDZ2 |
| Pfam | PF12130; PF00307; PF01494; PF00412 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in the thymus, lung, spleen, kidney, testis and hematopoietic cells. {ECO:0000269|PubMed:11827972}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.004323(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1WYL (NMR - ) 2CO8 (NMR - ) 2DK9 (NMR - ) 5LE0 (X-ray 3.30A ) 5LPN (X-ray 2.80A ) 6KU0 (X-ray 1.60A ) |
| DBSNP | rs4946977 rs4946977 rs34726911 rs34699467 rs17854785 rs17850590 rs9320288 rs35260632 rs59056467 rs59056467 |
| Subcellular location [CC] | Cytoplasm. Cytoplasm, cytoskeleton. Midbody {ECO:0000269|PubMed:28230050}. Note=Accumulates transiently at the abscission site before abscission occurs. {ECO:0000269|PubMed:28230050}. |
| Mouse PG classification | NA |
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