| Gene Information | |
|---|---|
| Gene Name | MSMB |
| Organism | Homo sapiens (Human) |
| Gene Length | 114 |
| Protein Names | Beta-microseminoprotein (Immunoglobulin-binding factor) (IGBF) (PN44) (Prostate secreted seminal plasma protein) (Prostate secretory protein of 94 amino acids) (PSP-94) (PSP94) (Seminal plasma beta-inhibin) |
| Target Name | beta-microseminoprotein |
| Target Type | Clinical trial target |
| Gene Age | 454 ( ENSG00000263639 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P08118 |
| Gene Card | MSMB |
| Uniprot ID | P08118 |
| Pfam | PF05825 |
| In ASD | no |
| Allosteric Prediction | no (-0.915924283) |
| Ortholog in Animals | Alpaca_ MSMB ( ortholog_one2one ) Macaque_ MSMB ( ortholog_one2one ) Mouse_ Msmb ( ortholog_one2one ) Pig_ MSMB ( ortholog_one2one ) Rat_ Msmb ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | MSMP |
| Tissue | prostate, lung, small.intestine |
| Tissue Specificity | Strongly expressed in prostate, liver, kidney, breast and penis. Also expressed in pancreas, esophagus, stomach, deodenum, colon, trachea, lung, salivary glands and fallopian tube. PSP94 is expressed in lung and breast, whereas PSP57 is found in kidney and bladder. {ECO:0000269|PubMed:7566962, ECO:0000269|PubMed:7671139}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2IZ3 (NMR - ) 3IX0 (X-ray 2.30A ) |
| DBSNP | rs1804776 rs1804778 rs1804780 rs1804468 rs1802774 rs1802771 rs1804469 rs1804461 rs1804464 |
| Subcellular location [CC] | Secreted. Note=Sperm surface. |
| Mouse PG classification | NA |
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