| Gene Information | |
|---|---|
| Gene Name | EGR2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 476 |
| Protein Names | E3 SUMO-protein ligase EGR2 (EC 2.3.2.-) (AT591) (E3 SUMO-protein transferase ERG2) (Early growth response protein 2) (EGR-2) (Zinc finger protein Krox-20) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000122877 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | P11161 |
| Gene Card | EGR2 |
| Uniprot ID | P11161 |
| Pfam | PF11928; PF00096 |
| In ASD | no |
| Allosteric Prediction | yes (0.198628852) |
| Ortholog in Animals | Alpaca_ EGR2 ( ortholog_one2one ) Dog_ EGR2 ( ortholog_one2one ) GuineaPig_ EGR2 ( ortholog_one2one ) Macaque_ EGR2 ( ortholog_one2one ) Mouse_ Egr2 ( ortholog_one2one ) Pig_ EGR2 ( ortholog_one2one ) Rat_ Egr2 ( ortholog_one2one ) Rabbit_ EGR2 ( ortholog_one2one ) |
| Ohnologs | EGR1, EGR3 |
| Paralogs | EGR3, WT1, EGR4, EGR1 |
| Tissue | tibial.nerve |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs104894158 rs1589080611 rs104894161 rs1589080524 rs281865137 rs104894160 rs281865139 rs104894159 rs749558026 rs121434563 |
| Subcellular location [CC] | Nucleus {ECO:0000250|UniProtKB:P08152}. |
| Mouse PG classification | NA |
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