Gene Information
Gene NameMSHR
OrganismHomo sapiens (Human)
Gene Length317
Protein NamesMelanocyte-stimulating hormone receptor (MSH-R) (Melanocortin receptor 1) (MC1-R)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ01726
Gene CardMC1R
Uniprot IDQ01726
PfamPF00001
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityExpressed in melanocytes (PubMed:1325670, PubMed:31097585). Expressed in corticoadrenal tissue (PubMed:1325670). {ECO:0000269|PubMed:1325670, ECO:0000269|PubMed:31097585}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 7F4D  (EM  3.00A  7F4F  (EM  2.90A  7F4H  (EM  2.70A  7F4I  (EM  3.10A 
DBSNP rs200050206  rs748138541  rs766080391  rs1805005  rs34090186  rs1805006  rs34540312  rs2228479  rs34158934  rs2229617  rs33932559  rs201192930  rs374235260  rs11547464  rs1805007  rs1110400  rs3212365  rs104894524  rs104894523  rs1805008  rs885479  rs35040147  rs35784916  rs3212366  rs141177570  rs369542041  rs1805009 
Subcellular location [CC]Cell membrane {ECO:0000269|PubMed:31097585};
Multi-pass membrane protein {ECO:0000255}.
Mouse PG classificationNA
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