| Gene Information | |
|---|---|
| Gene Name | MSH4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 936 |
| Protein Names | MutS protein homolog 4 (hMSH4) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1714 ( ENSG00000057468 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O15457 |
| Gene Card | MSH4 |
| Uniprot ID | O15457 |
| Pfam | PF05188; PF05192; PF05190; PF00488 |
| In ASD | no |
| Allosteric Prediction | no (-0.371253131) |
| Ortholog in Animals | Alpaca_ MSH4 ( ortholog_one2one ) GuineaPig_ MSH4 ( ortholog_one2one ) Macaque_ MSH4 ( ortholog_one2one ) Mouse_ Msh4 ( ortholog_one2one ) Pig_ MSH4 ( ortholog_one2one ) Rat_ Msh4 ( ortholog_one2one ) Rabbit_ MSH4 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | MSH3, MSH2, MSH5, MSH6 |
| Tissue | testis |
| Tissue Specificity | Testis and ovary specific. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002657(Rat);0.033333(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs5745311 rs5745324 rs5745325 rs5745329 rs5745459 rs5745549 |
| Subcellular location [CC] | Chromosome {ECO:0000250|UniProtKB:Q99MT2}. |
| Mouse PG classification | NA |
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