| Gene Information | |
|---|---|
| Gene Name | MSF |
| Organism | Homo sapiens (Human) |
| Gene Length | 1404 |
| Protein Names | Proteoglycan 4 (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Cleaved into: Proteoglycan 4 C-terminal part] |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q92954 |
| Gene Card | PRG4 |
| Uniprot ID | Q92954 |
| Pfam | PF00045; PF01033 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Highly expressed in synovial tissue, cartilage and liver and weakly in heart and lung. Isoform B is expressed in kidney, lung, liver, heart and brain. Isoform C and isoform D are widely expressed. {ECO:0000269|PubMed:10545950, ECO:0000269|PubMed:11124536}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2273779 rs10158395 rs1293985 rs12134934 |
| Subcellular location [CC] | Secreted {ECO:0000269|PubMed:14976050, ECO:0000269|PubMed:32144329}. |
| Mouse PG classification | NA |
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