Gene Information
Gene NameMS4A4A
OrganismHomo sapiens (Human)
Gene Length239
Protein NamesMembrane-spanning 4-domains subfamily A member 4A (CD20 antigen-like 1) (Four-span transmembrane protein 1)
Target NameNA
Target TypeNA
Gene Age168 ( ENSG00000110079 )
Evolutionary StageEumetazoa
AlphaFoldDBQ96JQ5
Gene CardMS4A4A
Uniprot IDQ96JQ5
PfamPF04103
In ASDno
Allosteric Predictionno (-0.909461728)
Ortholog in AnimalsAlpaca_ MS4A4A ( ortholog_one2one )
Macaque_ MS4A4A ( ortholog_one2one )
Mouse_ Ms4a4d ( ortholog_many2many )
Mouse_ Ms4a4a ( ortholog_many2many )
Mouse_ Ms4a4c ( ortholog_many2many )
Mouse_ Ms4a4b ( ortholog_many2many )
Rat_ Ms4a4a ( ortholog_many2many )
Rat_ AABR07006275.1 ( ortholog_many2many )
Rat_ Ms4a4c ( ortholog_many2many )
Rat_ AABR07006278.1 ( ortholog_many2many )
OhnologsNA
ParalogsMS4A4E, MS4A12, MS4A6E, MS4A6A, MS4A7, MS4A10, MS4A2, MS4A1, MS4A8, MS4A15, TMEM212, MS4A13, MS4A5, MS4A18, MS4A3, MS4A14
TissueNA
Tissue SpecificityVariable expression in multiple hemopoietic cell lines.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs10750931  rs6591561  rs4644658 
Subcellular location [CC]Membrane;
Multi-pass membrane protein.
Mouse PG classificationNA
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