| Gene Information | |
|---|---|
| Gene Name | NLRC5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1866 |
| Protein Names | Protein NLRC5 (Caterpiller protein 16.1) (CLR16.1) (Nucleotide-binding oligomerization domain protein 27) (Nucleotide-binding oligomerization domain protein 4) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000140853 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q86WI3 |
| Gene Card | NLRC5 |
| Uniprot ID | Q86WI3 |
| Pfam | PF18461; PF12799; PF13516; PF05729; PF17776 |
| In ASD | no |
| Allosteric Prediction | no (-0.831931712) |
| Ortholog in Animals | Alpaca_ NLRC5 ( ortholog_one2one ) Dog_ NLRC5 ( ortholog_one2one ) GuineaPig_ NLRC5 ( ortholog_one2one ) Macaque_ NLRC5 ( ortholog_one2one ) Mouse_ Nlrc5 ( ortholog_one2one ) Pig_ NLRC5 ( ortholog_one2one ) Rat_ Nlrc5 ( ortholog_one2one ) Rabbit_ NLRC5 ( ortholog_one2one ) |
| Ohnologs | NLRC3, NLRP13, NOD1 |
| Paralogs | NLRP9, NLRP14, NLRP7, NLRP4, CIITA, NOD1, NLRP8, NLRP10, NLRP3, NLRP5, NLRP6, NLRP11, NLRP2, PYDC2, NLRC3, NLRX1, NLRP12, NLRP13, NLRP1, NOD2 |
| Tissue | adipose.tissue, spleen |
| Tissue Specificity | Expressed in spleen, thymus, lung, brain, tonsil, heart and prostate. {ECO:0000269|PubMed:20061403, ECO:0000269|PubMed:20434986}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs16965150 rs9938543 rs28438857 rs35534915 rs1672867 rs289723 rs7190199 rs7185320 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:20061403, ECO:0000269|PubMed:20434986}. |
| Mouse PG classification | NA |
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