| Gene Information | |
|---|---|
| Gene Name | MRAP2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 205 |
| Protein Names | Melanocortin-2 receptor accessory protein 2 (MC2R accessory protein 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000135324 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q96G30 |
| Gene Card | MRAP2 |
| Uniprot ID | Q96G30 |
| Pfam | PF15183 |
| In ASD | no |
| Allosteric Prediction | no (-0.407175082) |
| Ortholog in Animals | Alpaca_ MRAP2 ( ortholog_one2one ) Dog_ MRAP2 ( ortholog_one2one ) GuineaPig_ MRAP2 ( ortholog_one2one ) Mouse_ Mrap2 ( ortholog_one2one ) Pig_ MRAP2 ( ortholog_one2one ) Rat_ Mrap2 ( ortholog_one2one ) Rabbit_ MRAP2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in the adrenal gland and brain. Not expressed in other tissues. {ECO:0000269|PubMed:19329486}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs761868293 rs368589399 rs148904867 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:19329486}; Single-pass membrane protein {ECO:0000269|PubMed:19329486}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:19329486}; Single-pass membrane protein {ECO:0000269|PubMed:19329486}. Note=The formation of antiparallel homo- and heterodimers suggest that N- and C-terminus can both localize in the cytoplasmic and extracellular parts, depending on the context. {ECO:0000269|PubMed:20371771}. |
| Mouse PG classification | NA |
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