| Gene Information | |
|---|---|
| Gene Name | CLCNKB |
| Organism | Homo sapiens (Human) |
| Gene Length | 687 |
| Protein Names | Chloride channel protein ClC-Kb (Chloride channel Kb) (ClC-K2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 382 ( ENSG00000184908 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | P51801 |
| Gene Card | CLCNKB |
| Uniprot ID | P51801 |
| Pfam | PF00571; PF00654 |
| In ASD | no |
| Allosteric Prediction | no (-0.470533602) |
| Ortholog in Animals | Alpaca_ CLCNKB ( ortholog_one2one ) Macaque_ CLCNKB ( ortholog_one2one ) Mouse_ Clcnkb ( ortholog_many2many ) Mouse_ Clcnka ( ortholog_many2many ) Rat_ Clcnka ( ortholog_many2many ) Rat_ Clcnkb ( ortholog_many2many ) |
| Ohnologs | CLCN2, CLCN1 |
| Paralogs | CLCNKA, CLCN6, CLCN3, CLCN5, CLCN1, CLCN7, CLCN4, CLCN2 |
| Tissue | kidney, cortex.of.kidney |
| Tissue Specificity | Expressed predominantly in the kidney. {ECO:0000269|PubMed:11734858}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs34851419 rs2015352 rs5256 rs35530360 rs121909131 rs5259 rs121909132 rs1889789 rs7367494 rs5251 rs121909134 rs34255952 rs6650119 rs121909135 rs121909133 rs12140311 rs5253 rs2275166 rs5255 |
| Subcellular location [CC] | Cell membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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