| Gene Information | |
|---|---|
| Gene Name | KATNB1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 655 |
| Protein Names | Katanin p80 WD40 repeat-containing subunit B1 (Katanin p80 subunit B1) (p80 katanin) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000140854 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q9BVA0 |
| Gene Card | KATNB1 |
| Uniprot ID | Q9BVA0 |
| Pfam | PF13925; PF00400 |
| In ASD | no |
| Allosteric Prediction | no (-0.719839374) |
| Ortholog in Animals | Alpaca_ KATNB1 ( ortholog_one2one ) Dog_ KATNB1 ( ortholog_one2one ) GuineaPig_ KATNB1 ( ortholog_one2one ) Macaque_ KATNB1 ( ortholog_one2one ) Mouse_ Katnb1 ( ortholog_one2one ) Pig_ KATNB1 ( ortholog_one2one ) Rat_ Katnb1 ( ortholog_one2one ) Rabbit_ KATNB1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.066667(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs730880259 rs60158050 rs730880257 rs730880258 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:26929214, ECO:0000269|PubMed:9658175}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:16203747, ECO:0000269|PubMed:9568719}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000269|PubMed:16203747, ECO:0000269|PubMed:26929214, ECO:0000269|PubMed:9658175}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:9568719, ECO:0000269|PubMed:9658175}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:26929214}. Note=Predominantly cytoplasmic. Localized to the interphase centrosome and mitotic spindle poles (PubMed:9658175). Localizes within the cytoplasm, partially overlapping with microtubules, in interphase and to the mitotic spindle and spindle poles during mitosis (PubMed:26929214). {ECO:0000269|PubMed:26929214, ECO:0000269|PubMed:9658175}. |
| Mouse PG classification | HPG |
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