| Gene Information | |
|---|---|
| Gene Name | MRP3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1527 |
| Protein Names | ATP-binding cassette sub-family C member 3 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Canalicular multispecific organic anion transporter 2) (Multi-specific organic anion transporter D) (MOAT-D) (Multidrug resistance-associated protein 3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | O15438 |
| Gene Card | ABCC3 |
| Uniprot ID | O15438 |
| Pfam | PF00664; PF00005 |
| In ASD | yes |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Mainly expressed in the liver. Also expressed in small intestine, colon, prostate, testis, brain and at a lower level in the kidney. {ECO:0000269|PubMed:10094960, ECO:0000269|PubMed:15083066, ECO:0000269|PubMed:9738950}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs11568609 rs11568605 rs144520783 rs11568593 rs11568591 rs11568590 rs45461799 |
| Subcellular location [CC] | Basolateral cell membrane {ECO:0000269|PubMed:10094960, ECO:0000269|PubMed:10359813, ECO:0000269|PubMed:15083066}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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