| Gene Information | |
|---|---|
| Gene Name | MRP2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1545 |
| Protein Names | ATP-binding cassette sub-family C member 2 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (Canalicular multidrug resistance protein) (Canalicular multispecific organic anion transporter 1) (Multidrug resistance-associated protein 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q92887 |
| Gene Card | ABCC2 |
| Uniprot ID | Q92887 |
| Pfam | PF00664; PF00005 |
| In ASD | yes |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed by polarized cells in liver, kidney and intestine. The highest expression is found in liver. Expressed in small intestine (PubMed:28408210). {ECO:0000269|PubMed:28408210}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs927344 rs17222744 rs56131651 rs17222674 rs7080681 rs2273697 rs17222589 rs17222561 rs17216233 rs17222632 rs56199535 rs56220353 rs17222617 rs41318029 rs17222554 rs45441199 rs17222540 rs72558200 rs72558201 rs139188247 rs8187692 rs17222723 rs757141905 rs8187699 rs17216317 rs72558202 rs56296335 rs8187710 |
| Subcellular location [CC] | Apical cell membrane {ECO:0000269|PubMed:10220572, ECO:0000269|PubMed:11093739, ECO:0000269|PubMed:28408210}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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