| Gene Information | |
|---|---|
| Gene Name | NABP2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 211 |
| Protein Names | SOSS complex subunit B1 (Nucleic acid-binding protein 2) (Oligonucleotide/oligosaccharide-binding fold-containing protein 2B) (Sensor of single-strand DNA complex subunit B1) (Sensor of ssDNA subunit B1) (SOSS-B1) (Single-stranded DNA-binding protein 1) (hSSB1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000139579 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9BQ15 |
| Gene Card | NABP2 |
| Uniprot ID | Q9BQ15 |
| Pfam | PF01336 |
| In ASD | no |
| Allosteric Prediction | no (-0.921764942) |
| Ortholog in Animals | Alpaca_ NABP2 ( ortholog_one2one ) Dog_ NABP2 ( ortholog_one2one ) GuineaPig_ NABP2 ( ortholog_one2one ) Macaque_ NABP2 ( ortholog_one2one ) Mouse_ Nabp2 ( ortholog_one2one ) Pig_ NABP2 ( ortholog_one2one ) Rat_ Nabp2 ( ortholog_one2one ) Rabbit_ NABP2 ( ortholog_one2one ) |
| Ohnologs | NABP1 |
| Paralogs | NABP1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.05(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4OWT (X-ray 2.00A ) 4OWW (X-ray 2.30A ) 4OWX (X-ray 2.30A ) 5D8E (X-ray 3.00A ) 5D8F (X-ray 2.35A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:18449195, ECO:0000269|PubMed:19605351, ECO:0000269|PubMed:19683501}. Note=Localizes to nuclear foci following DNA damage. Foci formation is not cell-cycle dependent. Partial colocalization with RAD51 after ionizing radiation treatment. |
| Mouse PG classification | NA |
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