| Gene Information | |
|---|---|
| Gene Name | MRM3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 420 |
| Protein Names | rRNA methyltransferase 3, mitochondrial (EC 2.1.1.-) (16S rRNA (guanosine(1370)-2'-O)-methyltransferase) (16S rRNA [Gm1370] 2'-O-methyltransferase) (RNA methyltransferase-like protein 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000171861 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q9HC36 |
| Gene Card | MRM3 |
| Uniprot ID | Q9HC36 |
| Pfam | PF00588 |
| In ASD | no |
| Allosteric Prediction | no (-1.520383913) |
| Ortholog in Animals | Alpaca_ MRM3 ( ortholog_one2one ) Dog_ MRM3 ( ortholog_one2one ) GuineaPig_ MRM3 ( ortholog_one2one ) Macaque_ MRM3 ( ortholog_one2one ) Mouse_ Mrm3 ( ortholog_one2one ) Pig_ MRM3 ( ortholog_one2one ) Rat_ Mrm3 ( ortholog_one2one ) Rabbit_ MRM3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | TARBP1, MRM1 |
| Tissue | NA |
| Tissue Specificity | Expressed at same level in normal liver and hepatocarcinoma. {ECO:0000269|PubMed:12296377}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001899(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7OI6 (EM 5.70A ) |
| DBSNP | rs2273454 rs2249542 rs17854653 rs35780267 |
| Subcellular location [CC] | Mitochondrion {ECO:0000269|PubMed:24036117, ECO:0000269|PubMed:25009282}. |
| Mouse PG classification | NA |
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