| Gene Information | |
|---|---|
| Gene Name | MRM2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 246 |
| Protein Names | rRNA methyltransferase 2, mitochondrial (EC 2.1.1.-) (16S rRNA (uridine(1369)-2'-O)-methyltransferase) (16S rRNA [Um1369] 2'-O-methyltransferase) (Protein ftsJ homolog 2) |
| Target Name | mitochondrial rrna methyltransferase 2 |
| Target Type | Successful target |
| Gene Age | 1064 ( ENSG00000122687 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q9UI43 |
| Gene Card | MRM2 |
| Uniprot ID | Q9UI43 |
| Pfam | PF01728 |
| In ASD | no |
| Allosteric Prediction | no (-1.885967288) |
| Ortholog in Animals | Alpaca_ MRM2 ( ortholog_one2one ) Dog_ MRM2 ( ortholog_one2one ) GuineaPig_ MRM2 ( ortholog_one2one ) Macaque_ MRM2 ( ortholog_one2one ) Mouse_ Mrm2 ( ortholog_one2one ) Pig_ MRM2 ( ortholog_one2one ) Rat_ Mrm2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | FTSJ1, FTSJ3 |
| Tissue | NA |
| Tissue Specificity | Widely expressed, with highest expression in muscle, placenta, and heart. {ECO:0000269|PubMed:11827451}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2NYU (X-ray 1.76A ) 7O9K (EM 3.10A ) 7O9M (EM 2.50A ) 7ODS (EM 3.10A ) |
| DBSNP | NA |
| Subcellular location [CC] | Mitochondrion {ECO:0000269|PubMed:24036117, ECO:0000269|PubMed:25009282}. |
| Mouse PG classification | NA |
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