| Gene Information | |
|---|---|
| Gene Name | MRI |
| Organism | Homo sapiens (Human) |
| Gene Length | 157 |
| Protein Names | Cell cycle regulator of non-homologous end joining (Cell cycle regulator of NHEJ) (Modulator of retrovirus infection homolog) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9BWK5 |
| Gene Card | CYREN |
| Uniprot ID | Q9BWK5 |
| Pfam | PF15325 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6TYU (X-ray 1.47A ) |
| DBSNP | rs776124276 |
| Subcellular location [CC] | [Isoform 1]: Cytoplasm {ECO:0000269|PubMed:24610814}. Nucleus {ECO:0000269|PubMed:24610814}. Chromosome {ECO:0000269|PubMed:27063109}. Note=Nuclear localization may depend upon interaction with XRCC5/Ku80 and XRCC6/Ku70 heterodimer (PubMed:24610814). Localizes to DNA damage sites (PubMed:27063109). {ECO:0000269|PubMed:24610814, ECO:0000269|PubMed:27063109}.; [Isoform 3]: Cytoplasm {ECO:0000269|PubMed:24610814}. Note=Some nuclear localization may be due to passive diffusion. {ECO:0000269|PubMed:24610814}.; [Isoform 4]: Cytoplasm {ECO:0000269|PubMed:24610814}. Nucleus {ECO:0000269|PubMed:24610814}. Note=Nuclear localization may depend upon interaction with XRCC5/Ku80 and XRCC6/Ku70 heterodimer and increases upon etoposide treatment. {ECO:0000269|PubMed:24610814}. |
| Mouse PG classification | NA |
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