| Gene Information | |
|---|---|
| Gene Name | KIAA0910 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1573 |
| Protein Names | Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | O43426 |
| Gene Card | SYNJ1 |
| Uniprot ID | O43426 |
| Pfam | PF08952; PF03372; PF02383 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Concentrated at clathrin-coated endocytic intermediates in nerve terminals. Isoform 1 is more enriched than isoform 2 in developing brain as well as non-neuronal cells. Isoform 2 is very abundant in nerve terminals. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1W80 (X-ray 1.90A ) 2DNR (NMR - ) 2VJ0 (X-ray 1.60A ) 7A0V (X-ray 2.30A ) |
| DBSNP | rs398122403 rs2254562 rs1060499619 rs1057524877 rs115683257 rs9980589 rs769099271 rs2230767 |
| Subcellular location [CC] | Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:O18964}. |
| Mouse PG classification | NA |
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