Gene Information
Gene NameMPP8
OrganismHomo sapiens (Human)
Gene Length860
Protein NamesM-phase phosphoprotein 8 (Two hybrid-associated protein 3 with RanBPM) (Twa3)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ99549
Gene CardMPHOSPH8
Uniprot IDQ99549
PfamPF12796; PF13606; PF00385
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityNA
Pharmacological Animal Models0.000730(Chimpanzee);0.011588(Mouse);NULL(Rat);NULL(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 3LWE  (X-ray  2.05A  3QO2  (X-ray  2.49A  3R93  (X-ray  2.06A  3SVM  (X-ray  2.31A  6V2S  (X-ray  1.60A  7M5U  (X-ray  2.02A 
DBSNP NA 
Subcellular location [CC]Nucleus {ECO:0000269|PubMed:20871592, ECO:0000269|PubMed:23416073, ECO:0000269|PubMed:26022416, ECO:0000269|PubMed:28581500, ECO:0000269|PubMed:8885239}. Chromosome {ECO:0000269|PubMed:23416073, ECO:0000269|PubMed:26022416, ECO:0000269|PubMed:28581500}. Note=Detected on heterochromatin (PubMed:20871592, PubMed:26022416). Dissociates from chromatin during interphase and early mitosis (PubMed:23416073). Detected on nucleosomes (PubMed:20871592). {ECO:0000269|PubMed:20871592, ECO:0000269|PubMed:23416073, ECO:0000269|PubMed:26022416}.
Mouse PG classificationNA
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