| Gene Information | |
|---|---|
| Gene Name | ALKBH4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 302 |
| Protein Names | Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4 (Alkylated DNA repair protein alkB homolog 4) (DNA N6-methyl adenine demethylase ALKBH4) (EC 1.14.11.51) (Lysine-specific demethylase ALKBH4) (EC 1.14.11.-) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000160993 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9NXW9 |
| Gene Card | ALKBH4 |
| Uniprot ID | Q9NXW9 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-1.215571606) |
| Ortholog in Animals | Alpaca_ ALKBH4 ( ortholog_one2many ) Dog_ ALKBH4 ( ortholog_one2one ) GuineaPig_ ALKBH4 ( ortholog_one2one ) Macaque_ ALKBH4 ( ortholog_one2one ) Mouse_ Alkbh4 ( ortholog_one2one ) Pig_ ALKBH4 ( ortholog_one2one ) Rat_ Alkbh4 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Widely expressed, with highest expression in pancreas, ovary and spleen. {ECO:0000269|PubMed:17979886}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs41275227 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:17979886}. Nucleus {ECO:0000269|PubMed:17979886, ECO:0000269|PubMed:23145062}. Nucleus, nucleolus {ECO:0000250|UniProtKB:Q9D8F1}. Midbody {ECO:0000269|PubMed:23673617}. Note=Associates with the contractile ring and midbody. {ECO:0000269|PubMed:23673617}. |
| Mouse PG classification | NA |
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