| Gene Information | |
|---|---|
| Gene Name | ICE1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 2266 |
| Protein Names | Little elongation complex subunit 1 (Interactor of little elongator complex ELL subunit 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000164151 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9Y2F5 |
| Gene Card | ICE1 |
| Uniprot ID | Q9Y2F5 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-0.345379124) |
| Ortholog in Animals | Alpaca_ ICE1 ( ortholog_one2one ) Dog_ ICE1 ( ortholog_one2one ) Macaque_ ICE1 ( ortholog_one2one ) Mouse_ Ice1 ( ortholog_one2one ) Pig_ ICE1 ( ortholog_one2one ) Rat_ Ice1 ( ortholog_one2one ) Rabbit_ ICE1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PAFAH1B2, PAFAH1B3 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.032198(Chimpanzee);0.039539(Mouse);NULL(Rat);0.057143(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2619844 rs10475299 rs2578500 rs3806873 rs3806874 rs10065646 rs3747731 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:22195968, ECO:0000269|PubMed:23932780}. Nucleus, Cajal body {ECO:0000269|PubMed:23932780}. Note=Colocalizes with COIL in subnuclear Cajal and histone locus bodies. Associates to transcriptionally active chromatin at snRNA genes. {ECO:0000269|PubMed:23932780}. |
| Mouse PG classification | NA |
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