| Gene Information | |
|---|---|
| Gene Name | TLE3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 772 |
| Protein Names | Transducin-like enhancer protein 3 (Enhancer of split groucho-like protein 3) (ESG3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000140332 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q04726 |
| Gene Card | TLE3 |
| Uniprot ID | Q04726 |
| Pfam | PF03920; PF00400 |
| In ASD | no |
| Allosteric Prediction | yes (0.180043689) |
| Ortholog in Animals | Alpaca_ TLE3 ( ortholog_one2one ) Dog_ TLE3 ( ortholog_one2one ) GuineaPig_ TLE3 ( ortholog_one2one ) Macaque_ TLE3 ( ortholog_one2one ) Mouse_ Tle3 ( ortholog_one2one ) Pig_ TLE3 ( ortholog_one2one ) Rat_ Tle3 ( ortholog_one2one ) Rabbit_ TLE3 ( ortholog_one2one ) |
| Ohnologs | TLE2, TLE4, TLE1 |
| Paralogs | TLE6, TLE5, TLE1, TLE7, TLE2, TLE4 |
| Tissue | NA |
| Tissue Specificity | Placenta and lung. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.025(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1057864 |
| Subcellular location [CC] | Nucleus. |
| Mouse PG classification | NA |
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