| Gene Information | |
|---|---|
| Gene Name | MPP2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 763 |
| Protein Names | Forkhead box protein M1 (Forkhead-related protein FKHL16) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HFH-11) (HNF-3/fork-head homolog 11) (M-phase phosphoprotein 2) (MPM-2 reactive phosphoprotein 2) (Transcription factor Trident) (Winged-helix factor from INS-1 cells) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000108852 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q08050 |
| Gene Card | FOXM1 |
| Uniprot ID | Q08050 |
| Pfam | PF00250 |
| In ASD | no |
| Allosteric Prediction | no (-0.22624421) |
| Ortholog in Animals | Alpaca_ MPP2 ( ortholog_one2one ) Dog_ MPP2 ( ortholog_one2one ) GuineaPig_ MPP2 ( ortholog_one2one ) Macaque_ MPP2 ( ortholog_one2one ) Mouse_ Mpp2 ( ortholog_one2one ) Pig_ MPP2 ( ortholog_one2one ) Rat_ Mpp2 ( ortholog_one2one ) Rabbit_ MPP2 ( ortholog_one2one ) |
| Ohnologs | PALS2 |
| Paralogs | MPP3, MPP7, PALS1, CASK, PALS2, MPP1, MPP4 |
| Tissue | cerebral.cortex, testis |
| Tissue Specificity | Expressed in thymus, testis, small intestine, colon followed by ovary. Appears to be expressed only in adult organs containing proliferating/cycling cells or in response to growth factors. Also expressed in epithelial cell lines derived from tumors. Not expressed in resting cells. Isoform 2 is highly expressed in testis. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 3G73 (X-ray 2.21A ) 7FJ2 (X-ray 3.10A ) |
| DBSNP | rs28990715 rs28919868 rs3742076 rs28919869 rs28919870 |
| Subcellular location [CC] | Nucleus. |
| Mouse PG classification | NA |
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