| Gene Information | |
|---|---|
| Gene Name | MPP1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 466 |
| Protein Names | 55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000130830 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q00013 |
| Gene Card | MPP1 |
| Uniprot ID | Q00013 |
| Pfam | PF00625; PF00595; PF00018 |
| In ASD | no |
| Allosteric Prediction | no (-0.102204205) |
| Ortholog in Animals | Alpaca_ MPP1 ( ortholog_one2many ) Dog_ MPP1 ( ortholog_one2one ) GuineaPig_ MPP1 ( ortholog_one2one ) Macaque_ MPP1 ( ortholog_one2one ) Mouse_ Mpp1 ( ortholog_one2one ) Rabbit_ MPP1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | MPP3, MPP7, MPP2, PALS1, CASK, PALS2, MPP4 |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:17584769}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2EJY (NMR - ) 2EV8 (NMR - ) 3NEY (X-ray 2.26A ) |
| DBSNP | rs14092 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:19144871}; Lipid-anchor {ECO:0000305|PubMed:1713685}. Cell projection, stereocilium {ECO:0000250|UniProtKB:P70290}. Note=Colocalizes with WHRN at stereocilium tip during hair cell development (By similarity). Colocalizes with PALS1 in the retina, at the outer limiting membrane (OLM) (By similarity). Colocalizes with WHRN in the retina, at the outer limiting membrane (OLM), outer plexifirm layer (OPL), basal bodies and at the connecting cilium (CC) (By similarity). Colocalizes with NF2 in non-myelin-forming Schwann cells (PubMed:19144871). {ECO:0000250|UniProtKB:P70290, ECO:0000269|PubMed:19144871}. |
| Mouse PG classification | NA |
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