| Gene Information | |
|---|---|
| Gene Name | MPI |
| Organism | Homo sapiens (Human) |
| Gene Length | 423 |
| Protein Names | Mannose-6-phosphate isomerase (EC 5.3.1.8) (Phosphohexomutase) (Phosphomannose isomerase) (PMI) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000178802 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | P34949 |
| Gene Card | MPI |
| Uniprot ID | P34949 |
| Pfam | PF01238; PF20511; PF20512 |
| In ASD | no |
| Allosteric Prediction | yes (0.251517421) |
| Ortholog in Animals | Alpaca_ MPI ( ortholog_one2one ) Dog_ MPI ( ortholog_one2one ) GuineaPig_ MPI ( ortholog_one2one ) Macaque_ MPI ( ortholog_one2one ) Mouse_ Mpi ( ortholog_one2one ) Pig_ MPI ( ortholog_one2one ) Rat_ Mpi ( ortholog_one2one ) Rabbit_ MPI ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in all tissues, but more abundant in heart, brain and skeletal muscle. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs764835081 rs104894494 rs887249336 rs566620411 rs104894495 rs773678732 rs766458792 rs104894489 rs748090636 rs28928906 rs369326210 rs863225087 |
| Subcellular location [CC] | Cytoplasm {ECO:0000305}. |
| Mouse PG classification | LPG |
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