| Gene Information | |
|---|---|
| Gene Name | HTATIP2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 242 |
| Protein Names | Oxidoreductase HTATIP2 (EC 1.1.1.-) (30 kDa HIV-1 TAT-interacting protein) (HIV-1 TAT-interactive protein 2) |
| Target Name | oxidoreductase htatip2 |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000109854 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q9BUP3 |
| Gene Card | HTATIP2 |
| Uniprot ID | Q9BUP3 |
| Pfam | PF13460 |
| In ASD | no |
| Allosteric Prediction | no (-0.601902954) |
| Ortholog in Animals | Alpaca_ HTATIP2 ( ortholog_one2one ) Dog_ HTATIP2 ( ortholog_one2one ) GuineaPig_ HTATIP2 ( ortholog_one2one ) Mouse_ Htatip2 ( ortholog_one2one ) Pig_ HTATIP2 ( ortholog_one2one ) Rat_ Htatip2 ( ortholog_one2one ) Rabbit_ HTATIP2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. Highest level in liver. High levels in lung, skeletal muscle, pancreas and placenta. Moderate levels in heart and kidney. Low levels in brain. Not expressed or low levels in variant small cell lung carcinomas, 33% of hepatocellular carcinomas and neuroblastomas. {ECO:0000269|PubMed:14695192, ECO:0000269|PubMed:9174052}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2BKA (X-ray 1.70A ) |
| DBSNP | rs761113892 rs3824886 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:15282309}. Nucleus envelope {ECO:0000269|PubMed:15282309}. |
| Mouse PG classification | NA |
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