| Gene Information | |
|---|---|
| Gene Name | FNTB |
| Organism | Homo sapiens (Human) |
| Gene Length | 437 |
| Protein Names | Protein farnesyltransferase subunit beta (FTase-beta) (EC 2.5.1.58) (CAAX farnesyltransferase subunit beta) (Ras proteins prenyltransferase subunit beta) |
| Target Name | caax farnesyltransferase beta |
| Target Type | Literature-reported target |
| Gene Age | >4290 ( ENSG00000257365 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P49356 |
| Gene Card | FNTB |
| Uniprot ID | P49356 |
| Pfam | PF00432 |
| In ASD | no |
| Allosteric Prediction | yes (0.309609858) |
| Ortholog in Animals | Alpaca_ FNTB ( ortholog_one2one ) Dog_ FNTB ( ortholog_one2one ) GuineaPig_ FNTB ( ortholog_one2one ) Macaque_ FNTB ( ortholog_one2one ) Mouse_ Fntb ( ortholog_one2one ) Pig_ FNTB ( ortholog_one2one ) Rat_ Churc1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | RABGGTB, PGGT1B |
| Tissue | substantia.nigra, testis, zone.of.skin |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1JCQ (X-ray 2.30A ) 1LD7 (X-ray 2.00A ) 1LD8 (X-ray 1.80A ) 1MZC (X-ray 2.00A ) 1S63 (X-ray 1.90A ) 1SA4 (X-ray 2.10A ) 1TN6 (X-ray 1.80A ) 2F0Y (X-ray 2.70A ) 2H6F (X-ray 1.50A ) 2H6G (X-ray 1.85A ) 2H6H (X-ray 1.80A ) 2H6I (X-ray 3.00A ) 2IEJ (X-ray 1.80A ) 3E37 (X-ray 1.80A ) |
| DBSNP | NA |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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