Gene Information
Gene NameMPD
OrganismHomo sapiens (Human)
Gene Length400
Protein NamesDiphosphomevalonate decarboxylase (EC 4.1.1.33) (Mevalonate (diphospho)decarboxylase) (MDDase) (Mevalonate pyrophosphate decarboxylase)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBP53602
Gene CardMVD
Uniprot IDP53602
PfamPF00288; PF18376
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityExpressed in heart, skeletal muscle, lung, liver, brain, pancreas, kidney and placenta. {ECO:0000269|PubMed:8626466}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 3D4J  (X-ray  2.40A 
DBSNP rs200033380  rs776358937  rs144010349  rs770939767  rs776684503  rs761991070  rs34519538  rs755948940  rs764836183  rs546127665 
Subcellular location [CC]Cytoplasm {ECO:0000269|PubMed:14972328}.
Mouse PG classificationNA
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