| Gene Information | |
|---|---|
| Gene Name | GPT2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 523 |
| Protein Names | Alanine aminotransferase 2 (ALT2) (EC 2.6.1.2) (Glutamate pyruvate transaminase 2) (GPT 2) (Glutamic--alanine transaminase 2) (Glutamic--pyruvic transaminase 2) |
| Target Name | alanine aminotransferase 2 |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000166123 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q8TD30 |
| Gene Card | GPT2 |
| Uniprot ID | Q8TD30 |
| Pfam | PF00155 |
| In ASD | no |
| Allosteric Prediction | yes (0.634627031) |
| Ortholog in Animals | Alpaca_ GPT2 ( ortholog_one2one ) GuineaPig_ GPT2 ( ortholog_one2one ) Macaque_ GPT2 ( ortholog_one2one ) Mouse_ Gpt2 ( ortholog_one2one ) Pig_ GPT2 ( ortholog_one2one ) Rat_ Gpt2 ( ortholog_one2one ) Rabbit_ GPT2 ( ortholog_one2one ) |
| Ohnologs | GPT |
| Paralogs | ACCS, AADAT, KYAT3, TAT, KYAT1, ACCSL, GPT |
| Tissue | NA |
| Tissue Specificity | Expressed at high levels in muscle, adipose tissue, kidney and brain and at lower levels in the liver and breast. {ECO:0000269|PubMed:11863375}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.105263(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3IHJ (X-ray 2.30A ) |
| DBSNP | rs786203999 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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