| Gene Information | |
|---|---|
| Gene Name | DPP10 |
| Organism | Homo sapiens (Human) |
| Gene Length | 796 |
| Protein Names | Inactive dipeptidyl peptidase 10 (Dipeptidyl peptidase IV-related protein 3) (DPRP-3) (Dipeptidyl peptidase X) (DPP X) (Dipeptidyl peptidase-like protein 2) (DPL2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000175497 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q8N608 |
| Gene Card | DPP10 |
| Uniprot ID | Q8N608 |
| Pfam | PF00930; PF00326 |
| In ASD | no |
| Allosteric Prediction | yes (0.031160995) |
| Ortholog in Animals | Alpaca_ DPP10 ( ortholog_one2one ) Dog_ DPP10 ( ortholog_one2one ) GuineaPig_ DPP10 ( ortholog_one2one ) Macaque_ DPP10 ( ortholog_one2one ) Mouse_ Dpp10 ( ortholog_one2one ) Pig_ DPP10 ( ortholog_one2one ) Rat_ Dpp10 ( ortholog_one2one ) Rabbit_ DPP10 ( ortholog_one2one ) |
| Ohnologs | DPP6 |
| Paralogs | APEH, FAP, DPP8, DPP6, DPP9, DPP4 |
| Tissue | adrenal.gland, brain |
| Tissue Specificity | Found in serum, T-cells and brain (at protein level). Expressed in brain, pancreas, spinal cord and adrenal glands. {ECO:0000269|PubMed:12662155, ECO:0000269|PubMed:14566338}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4WJL (X-ray 3.40A ) |
| DBSNP | rs2053724 rs1446495 rs13421193 |
| Subcellular location [CC] | Cell membrane {ECO:0000250|UniProtKB:Q6NXK7, ECO:0000269|PubMed:14566338}; Single-pass type II membrane protein {ECO:0000250|UniProtKB:P42658}. |
| Mouse PG classification | NA |
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