| Gene Information | |
|---|---|
| Gene Name | MOK |
| Organism | Homo sapiens (Human) |
| Gene Length | 419 |
| Protein Names | MAPK/MAK/MRK overlapping kinase (EC 2.7.11.22) (MOK protein kinase) (Renal tumor antigen 1) (RAGE-1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000080823 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9UQ07 |
| Gene Card | MOK |
| Uniprot ID | Q9UQ07 |
| Pfam | PF00069 |
| In ASD | no |
| Allosteric Prediction | no (-0.516345897) |
| Ortholog in Animals | Alpaca_ MOK ( ortholog_one2one ) Dog_ MOK ( ortholog_one2one ) Macaque_ MOK ( ortholog_one2one ) Mouse_ Mok ( ortholog_one2one ) Pig_ MOK ( ortholog_one2one ) Rat_ Mok ( ortholog_one2one ) Rabbit_ MOK ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | MAPK8, MAPK10, MAPK1, MAPK6, MAPK12, MAPK13, SRPK1, SRPK3, MAPK4, NLK, MAPK14, MAPK3, MAPK11, MAK, MAPK15, MAPK7, SRPK2, MAPK9, CILK1 |
| Tissue | NA |
| Tissue Specificity | Expressed in heart, brain, lung, kidney, and pancreas, and at very low levels in placenta, liver and skeletal muscle. Detected in retina. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs34114580 rs34084056 rs148360666 rs34965156 rs34299975 rs1567133856 rs2236493 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250|UniProtKB:Q9WVS4}. Cell projection, cilium {ECO:0000250|UniProtKB:Q9WVS4}. Nucleus {ECO:0000250|UniProtKB:Q9WVS4}. |
| Mouse PG classification | NA |
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