| Gene Information | |
|---|---|
| Gene Name | MOAP1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 351 |
| Protein Names | Modulator of apoptosis 1 (MAP-1) (MAP1) (Paraneoplastic antigen Ma4) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 36 ( ENSG00000165943 ) 3 ( ENSG00000278268 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q96BY2 |
| Gene Card | MOAP1 |
| Uniprot ID | Q96BY2 |
| Pfam | PF14893 |
| In ASD | no |
| Allosteric Prediction | no (-1.341396291) |
| Ortholog in Animals | Alpaca_ MOAP1 ( ortholog_one2one ) Macaque_ MOAP1 ( ortholog_one2one ) Mouse_ Moap1 ( ortholog_one2one ) Rat_ Moap1 ( ortholog_one2many ) |
| Ohnologs | NA |
| Paralogs | PNMA1, ZCCHC12, PNMA8C, PNMA2, PNMA6F, CCDC8, PNMA6A, PNMA3, PNMA8A, ZCCHC18, PNMA8B, PNMA6E, PNMA5 |
| Tissue | NA |
| Tissue Specificity | Widely expressed, with high levels in heart and brain. {ECO:0000269|PubMed:19366867}. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.070650(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7LGC (X-ray 1.85A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm, cytosol {ECO:0000269|PubMed:19100260}. Mitochondrion outer membrane {ECO:0000269|PubMed:16199525}. Extracellular vesicle membrane {ECO:0000250|UniProtKB:Q9ERH6}. Note=Forms virion-like extracellular vesicles that are released from cells. {ECO:0000250|UniProtKB:Q9ERH6}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |