| Gene Information | |
|---|---|
| Gene Name | MNS1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 495 |
| Protein Names | Meiosis-specific nuclear structural protein 1 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000138587 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8NEH6 |
| Gene Card | MNS1 |
| Uniprot ID | Q8NEH6 |
| Pfam | PF13868 |
| In ASD | no |
| Allosteric Prediction | no (-1.396216593) |
| Ortholog in Animals | Alpaca_ MNS1 ( ortholog_one2one ) Dog_ MNS1 ( ortholog_one2one ) GuineaPig_ MNS1 ( ortholog_one2one ) Macaque_ MNS1 ( ortholog_one2one ) Mouse_ Mns1 ( ortholog_one2one ) Pig_ MNS1 ( ortholog_one2one ) Rat_ Mns1 ( ortholog_one2one ) Rabbit_ MNS1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | testis, kidney |
| Tissue Specificity | Expressed in nasal respiratory epithelium and in the sperm. {ECO:0000269|PubMed:30148830}. |
| Pharmacological Animal Models | 0.062419(Chimpanzee);0.016779(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs34807682 rs1715919 rs35775595 rs17852882 rs17853357 |
| Subcellular location [CC] | Nucleus {ECO:0000250|UniProtKB:Q61884}. Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000269|PubMed:30148830}. Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000269|PubMed:30148830}. Note=Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme. {ECO:0000250|UniProtKB:Q2KIQ2}. |
| Mouse PG classification | NA |
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