| Gene Information | |
|---|---|
| Gene Name | MNF |
| Organism | Homo sapiens (Human) |
| Gene Length | 733 |
| Protein Names | Forkhead box protein K1 (Myocyte nuclear factor) (MNF) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P85037 |
| Gene Card | FOXK1 |
| Uniprot ID | P85037 |
| Pfam | PF00498; PF00250 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed both developing and adult tissues (PubMed:15289879). In adults, significant expression is seen in tumors of the brain, colon and lymph node (PubMed:15289879). {ECO:0000269|PubMed:15289879}. |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.001000(Mouse);0.002657(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:25805136, ECO:0000269|PubMed:25852164}. Cytoplasm {ECO:0000269|PubMed:25805136, ECO:0000269|PubMed:25852164}. Note=Translocation to the nucleus is regulated by phosphorylation: phosphorylation by GSK3 (GSK3A or GSK3B) promotes interaction with 14-3-3 proteins and sequestration in the cytoplasm. Dephosphorylation promotes translocation to the nucleus (By similarity). Accumulates in the nucleus upon viral infection (PubMed:25852164). {ECO:0000250|UniProtKB:P42128, ECO:0000269|PubMed:25852164}. |
| Mouse PG classification | NA |
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