| Gene Information | |
|---|---|
| Gene Name | EIF3A |
| Organism | Homo sapiens (Human) |
| Gene Length | 1382 |
| Protein Names | Eukaryotic translation initiation factor 3 subunit A (eIF3a) (Eukaryotic translation initiation factor 3 subunit 10) (eIF-3-theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000107581 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q14152 |
| Gene Card | EIF3A |
| Uniprot ID | Q14152 |
| Pfam | PF01399 |
| In ASD | no |
| Allosteric Prediction | yes (0.17077931) |
| Ortholog in Animals | Alpaca_ EIF3A ( ortholog_one2one ) Dog_ EIF3A ( ortholog_one2one ) GuineaPig_ EIF3A ( ortholog_one2one ) Macaque_ EIF3A ( ortholog_one2one ) Mouse_ Eif3a ( ortholog_one2one ) Pig_ EIF3A ( ortholog_one2one ) Rat_ Eif3a ( ortholog_one2one ) Rabbit_ EIF3A ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.072440(Rat);0.209156(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3J8B (EM - ) 3J8C (EM - ) 6YBD (EM 3.30A ) 6YBT (EM 6.00A ) 6ZMW (EM 3.70A ) 6ZON (EM 3.00A ) 6ZP4 (EM 2.90A ) 6ZVJ (EM 3.80A ) 7A09 (EM 3.50A ) 7QP6 (EM 4.70A ) 7QP7 (EM 3.70A ) |
| DBSNP | rs967185 rs431898 rs532138 |
| Subcellular location [CC] | Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03000, ECO:0000269|PubMed:9150439}. |
| Mouse PG classification | NA |
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