| Gene Information | |
|---|---|
| Gene Name | MNAB |
| Organism | Homo sapiens (Human) |
| Gene Length | 1191 |
| Protein Names | Roquin-2 (EC 2.3.2.27) (Membrane-associated nucleic acid-binding protein) (RING finger and CCCH-type zinc finger domain-containing protein 2) (RING finger protein 164) (RING-type E3 ubiquitin transferase Roquin-2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9HBD1 |
| Gene Card | RC3H2 |
| Uniprot ID | Q9HBD1 |
| Pfam | PF18386; PF00642 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in spleen, testis, ovary and small intestine. {ECO:0000269|PubMed:10938276}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.005405(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4Z30 (X-ray 2.71A ) 4Z31 (X-ray 2.50A ) 4ZLC (X-ray 2.70A ) 4ZLD (X-ray 1.60A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm, P-body {ECO:0000250}. Note=During stress, such as that induced by arsenite, localizes to cytosolic stress granules. Localization to stress granules, but not to P-bodies, depends upon the RING-type zinc finger. {ECO:0000269|PubMed:20412057}. |
| Mouse PG classification | NA |
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