| Gene Information | |
|---|---|
| Gene Name | MMUT |
| Organism | Homo sapiens (Human) |
| Gene Length | 750 |
| Protein Names | Methylmalonyl-CoA mutase, mitochondrial (MCM) (EC 5.4.99.2) (Methylmalonyl-CoA isomerase) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1064 ( ENSG00000146085 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | P22033 |
| Gene Card | MMUT |
| Uniprot ID | P22033 |
| Pfam | PF02310; PF01642 |
| In ASD | no |
| Allosteric Prediction | yes (0.449625875) |
| Ortholog in Animals | Alpaca_ MMUT ( ortholog_one2one ) Dog_ MMUT ( ortholog_one2one ) GuineaPig_ MMUT ( ortholog_one2one ) Macaque_ MMUT ( ortholog_one2one ) Mouse_ Mmut ( ortholog_one2one ) Pig_ MMUT ( ortholog_one2one ) Rat_ Mmut ( ortholog_one2one ) Rabbit_ MMUT ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | MMAA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.000730(Chimpanzee);NULL(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2XIJ (X-ray 1.95A ) 2XIQ (X-ray 1.95A ) 3BIC (X-ray 2.60A ) |
| DBSNP | rs115923556 rs769348060 rs1554160986 rs121918251 rs727504022 rs535411418 rs190834116 rs864309735 rs121918249 rs121918257 rs483352778 rs1461110052 rs796052005 rs879253827 rs879253828 rs941483851 rs941483851 rs879253829 rs1554160730 rs1300547552 rs757000253 rs864309733 rs148331800 rs879253830 rs200908035 rs1561959114 rs760782399 rs778702777 rs879253831 rs121918258 rs121918258 rs1446389693 rs121918256 rs770810987 rs879253833 rs864309736 rs12175488 rs796052007 rs879253835 rs761477436 rs1179778233 rs1554160246 rs1085307929 rs864309734 rs781474200 rs780387525 rs879253837 rs758577372 rs796052002 rs965316043 rs1026703654 rs1407914109 rs563776413 rs864309737 rs772552898 rs564069299 rs368790885 rs121918250 rs1554159937 rs866933356 rs766010704 rs879253840 rs879253842 rs533755473 rs769922244 rs753288303 rs2229385 rs864309738 rs1141321 rs760183775 rs879253845 rs1238333040 rs775593146 rs1554158951 rs9473556 rs1554158777 rs1302409621 rs765284825 rs1554158775 rs879253846 rs121918254 rs768521956 rs879253847 rs982110849 rs372486357 rs143023066 rs200055428 rs781501004 rs865815395 rs747897332 rs766721811 rs1360470463 rs8589 rs1164271240 rs147094927 rs864309739 rs777758903 rs140600746 rs121918255 rs121918252 rs755077681 rs753461919 |
| Subcellular location [CC] | Mitochondrion matrix {ECO:0000269|PubMed:24458}. Mitochondrion {ECO:0000269|PubMed:28943303}. Cytoplasm {ECO:0000269|PubMed:28943303}. |
| Mouse PG classification | NA |
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