| Gene Information | |
|---|---|
| Gene Name | MMP7 |
| Organism | Homo sapiens (Human) |
| Gene Length | 267 |
| Protein Names | Matrilysin (EC 3.4.24.23) (Matrin) (Matrix metalloproteinase-7) (MMP-7) (Pump-1 protease) (Uterine metalloproteinase) |
| Target Name | matrilysin |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000137673 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P09237 |
| Gene Card | MMP7 |
| Uniprot ID | P09237 |
| Pfam | PF00413; PF01471 |
| In ASD | yes |
| Allosteric Prediction | yes (1.000272807) |
| Ortholog in Animals | Alpaca_ MMP7 ( ortholog_one2one ) Dog_ MMP7 ( ortholog_one2one ) Macaque_ MMP7 ( ortholog_one2one ) Mouse_ Mmp7 ( ortholog_one2one ) Pig_ MMP7 ( ortholog_one2one ) Rat_ Mmp7 ( ortholog_one2one ) Rabbit_ MMP7 ( ortholog_one2one ) |
| Ohnologs | MMP25, MMP11, MMP15 |
| Paralogs | MMP24, MMP16, MMP21, MMP14, MMP2, MMP1, MMP19, MMP23B, MMP10, MMP9, MMP12, MMP15, MMP27, MMP17, MMP25, MMP28, MMP13, MMP20, MMP26, HPX, MMP8, MMP3, MMP11 |
| Tissue | cortex.of.kidney, minor.salivary.gland |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1MMP (X-ray 2.30A ) 1MMQ (X-ray 1.90A ) 1MMR (X-ray 2.40A ) 2DDY (NMR - ) 2MZE (NMR - ) 2MZH (NMR - ) 2MZI (NMR - ) 2Y6C (X-ray 1.70A ) 2Y6D (X-ray 1.60A ) 5UE2 (NMR - ) 5UE5 (NMR - ) |
| DBSNP | rs10502001 rs17884789 rs17886506 |
| Subcellular location [CC] | Secreted, extracellular space, extracellular matrix {ECO:0000305}. |
| Mouse PG classification | NA |
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