Gene Information
Gene NameMMP23B
OrganismHomo sapiens (Human)
Gene Length390
Protein NamesMatrix metalloproteinase-23 (MMP-23) (EC 3.4.24.-) (Femalysin) (MIFR-1) (Matrix metalloproteinase-21) (MMP-21) (Matrix metalloproteinase-22) (MMP-22) [Cleaved into: Matrix metalloproteinase-23, soluble form]
Target NameNA
Target TypeNA
Gene Age544 ( ENSG00000189409 )
Evolutionary StageVertebrata
AlphaFoldDBO75900
Gene CardMMP23B
Uniprot IDO75900
PfamPF00413; PF01549
In ASDno
Allosteric Predictionno (-0.597495485)
Ortholog in AnimalsAlpaca_ MMP23 ( ortholog_one2one )
Dog_ MMP23 ( ortholog_one2one )
Macaque_ MMP23 ( ortholog_one2one )
Mouse_ Mmp23 ( ortholog_one2one )
Pig_ MMP23B ( ortholog_one2one )
Rat_ Mmp23 ( ortholog_one2one )
OhnologsNA
ParalogsMMP24, MMP16, MMP21, MMP14, MMP2, MMP1, MMP19, MMP10, MMP9, MMP12, MMP15, MMP27, MMP17, MMP25, MMP28, MMP13, MMP7, MMP20, MMP26, HPX, MMP8, MMP3, MMP11
TissueNA
Tissue SpecificityPredominantly expressed in ovary, testis and prostate. {ECO:0000269|PubMed:9988691}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Endoplasmic reticulum membrane {ECO:0000250};
Single-pass type II membrane protein {ECO:0000250}. Membrane {ECO:0000269|PubMed:11328856};
Single-pass type II membrane protein {ECO:0000269|PubMed:11328856}. Note=A secreted form produced by proteolytic cleavage may also exist. {ECO:0000305}.
Mouse PG classificationNA
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